ATTIA: I did. But life isnt really about necessarily being the master of something. Were you a good fighter? So it might be another totally new way to tap benefit above and beyond the nighttime sleep. And we differentiate that form from the one that we evolved with by calling it nutritional ketosis. Non-lame, weekly emails on thelatest strategies and tacticsfor increasing your lifespan, healthspan, and well-being (plus new podcast announcements). We talk once every six months or four months. But I think there was a very similar insecurity. But when we sleep, its best for our bodies to be cold when we sleep cooler, we get more rejuvenating sleep. LEVITT: The set of things hes done to his body over time, in the spirit of self-experimentation, are mind-blowing. [5] He spent two years at the National Cancer Institute (NCI) at National Institutes of Health (NIH), in Bethesda, Maryland as a surgical oncology fellow under Steven Rosenberg. He also has a B.Sc. LEVITT: Thats been my reaction exactly, is, the answer to every one of the questions you just posed is completely and totally knowable. But it needs to be that long nap because thats about the length of time it takes to go through the phases of sleep. I also had an additional conversation with Kevin Hall, PhD, one of the key researchers NuSI . Peter Attia (born 19 March 1973) is a Canadian-American physician known for his medical practice that focuses on the science of longevity. And it sucked. I dont do such silly things anymore. From 2012-2015, he . Try playing chess with it, its so confident gives you a very detailed analysis why it's making a move and why your move was wrong, but tried to make illegal moves and doesn't So I just generally say try not to eat too much before bed. What Happened To Peter Attia. Physician. Peter Attia @PeterAttiaMD. Were not talking about inoculating someone with hepatitis or H.I.V. This magnesium features what's called an enteric coating to protect it from premature disintegration. Stay tuned for Wednesdays episode Part 2 of my interview with Dr. Peter Attia! Hes playing the long-game and working hard to maintain the strength and overall good health hell need to continue living an active and fulfilled life even when hes over 100 years old. But something inside said, You dont feel right. So I said, Hey, Mike, I got to call it a day, man. And when I went down to cool down by hitting the speed bag, which is that tiny little round bag that basically has no weight or impact just the impact of hitting that hurt my head so much that I was like, I got to stop.. Peter's current diet can simplified into 3 "rules": Time Restricted Feeding Avoid Sugars, High Fructose Corn Syrup & Junk Food No Restriction on Healthy Starches and Vegetables 1) Time Restricted Feeding At the low end, Peter fasts between 14 - 16 hours each day, and at the high end, he fasts between 20 - 22 hours. Now he's a physician focused on the science of longevity. My guest today is physician Dr. Peter Attia. ATTIA: So a big part of our clumsy response to this is that it couldnt be centrally coordinated. I am a physician focusing on the applied science of longevity. ATTIA: Well, rigidity of thinking is generally a bad thing. Every time I go to an academic seminar, Im going to bring two pieces of Nicorette gum. Its complicated because there are lots of reagents that go into that type of testing and we dont control the origin of each of those reagents. And these days I spend virtually no time in nutritional ketosis. And they have totally different mechanisms. In this operating manual for longevity, Dr. Peter Attia draws on the latest science to deliver innovative nutritional interventions, techniques for optimizing exercise and sleep, and tools for addressing emotional and mental health. I hope you loved this episode as much as I did. How we are going about medicine the wrong way. And that ketone was a substitute fuel for glucose and for fat. This is a tragedy. Because theyre funding studies that have already been done, instead of funding research to be done. I definitely had one horrible concussion. Peter Attia is a physician focusing on the applied science of longevity. Lets talk a little bit about the difference between lifespan and healthspan because theres a really key distinction between them. Peter Attia is a Canadian-born doctor who focuses on the science of longevity. When I first met you, that was your obsession, nutrition. Which diseases are killing people the most and what to do about it. Ive known Peter for 10 years. Welcome toPeople I (Mostly) Admirewith Steve Levitt. All rights reserved. You can really imagine the matrix of studies that needs to be done, which says, O.K., what does transmission look like inside versus outside? And while learning to manage stress and overcome trauma may not be the only thing it takes to prevent Type 2 diabetes, it will definitely increase your odds of staying healthy longer. I think there [are] basically three ways that we can approach dealing with this: One of these is through psychotherapy, pharmacotherapy, and then behavioral therapy, which Im an overwhelming proponent of in particular a type of behavioral therapy called Dialectical Behavioral Therapy or DBT. Dr. Peter Attia. And you might say, Well, gosh, thats a lot of money. But in the scope of things, thats a trivial sum of money, if we could actually know that this much fasting could extend not just life, but improve quality of life that much. We can be reached at radio@freakonomics.com. Well, I have six kids and I havent had a good nights sleep in 18 years. Now, whether its another SARS coronavirus or an influenza virus or another virus, I dont know. And I think its the perfect model, which is: let the government come in when its been de-risked. Matt Hickey is the producer, and Dan Dzula was the engineer of this episode. You sometimes need that distance from something. Now hes a physician focused on the science of longevity. ATTIA: Ive come a long way since then, Steve. Healthspan has three pieces, right? Its a wonderful fuel. He also receives speaking honorariums from organizations, including hospitals and health-related businesses, when he is asked to speak on longevity, metabolic-related topics, athletic performance, and his personal experience working in medicine. For all its successes, mainstream medicine has failed to make much progress against the diseases of aging that kill most people: heart disease, cancer, Alzheimers disease, and type 2 diabetes. How long? Whats the latest we should eat before going to bed? Its also the one that seemed the most conflicted. And I think youve come to appreciate, in recent years, the importance of sleep. Slow-Mag is designed to maximize mag's benefits while simultaneously minimizing its side effects. His post can be found here. ATTIA: I dont know if that exercise did, but yes, I think a lot of the training that I did did pay off, actually. I think once I was in medical school and I decided I wanted to become a surgeon, I just had this anxiety, which was, Well, what if you have to operate in the middle of the night and youre tired? So one of the things I started doing in my last year of medical school was, every Thursday night I would stay up, pull an all-nighter, stand at my desk, not allow myself to pee, and practice suturing on my desk in this model that I made that was supposed to resemble a human heart. By reducing the amount of carbohydrates we consume and by exercising, we reduce the amount of glucose were consuming and increase our muscle so that when we, consume glucose, our bodies have somewhere to put it. And for that, Dr. Peter recommended therapy. ATTIA: Well, I think its too soon to say that. Lets watch this thing instead. And shes like, Who is this guy? And I said, Look, I dont agree with half the things this guy says, but he is categorically one of the smartest dudes ever. And the more I learned, frankly, the less I agreed with him. And I dont think Im very good at it, Steve. I want to be able to pull myself out of a pool where theres a one-foot gap between the water and the curb. is who Id want for my doctor. And so many years later, as I began to actually understand the benefits of sleep, it stands alone as one of what I think of as one of the four or five pillars of longevity. And when my daughter was born, I ended up getting a type of medical test that had a finding that no one in their mid-thirties should have. But heres the problem: Were living longer, but our quality of life is decreasing. LEVITT: I will say that youve taught me a lot and I never told you this before youre one of the few people on the planet whose opinion I trust so completely that when you tell me to do something, no matter how absurd it sounds, I do it. Its the cognitive piece so how well does your brain work as you age? Its not about exercising. Part of the practice includes nutritional biochemistry, a field that deals with supplements. And to this day, we still respect each other greatly. If you take a 20-minute afternoon nap, youre not going to get into whats called delta wave sleep. And I religiously do whatever you tell me to do. Youll have to wait until Wednesday for Dr. Peters definition of greatness, so for now, Ill leave you with one final piece of wisdom: There are people out there who have so many genetic things working against them, that theyll be lucky to make it to 80. Lets dive in! in mechanical engineering and applied mathematics. Part 1. Apparently Peter and his buddy Gary Taubes just love themselves some crappy pseudoscience. Because what youre basically saying is: whats the dose? But I certainly didnt appreciate at the time what it was doing to my health. Please be respectful toward other contributors. Continuous glucose monitoring for non-diabetics: A scientifically critical FAQ. Comments that harass other posters will be deleted. But the probability, Steve, that you or I may get the rest of our lives without another pandemic must be viewed as exceedingly small. Which is: what are those people who cant quit also incapable of doing on a day to day basis, vis vis their very rigid view of, this is the way to do things versus not. And Im still generally a somewhat rigid person. The first two are simple: Diet and exercise. Have any hacks how to do? Throughout our lives, we experience different stressors that can cause strain on our mental health. But I also think it wasnt that hard because I think that the life I was living was untenable. And just to be clear, Im just the guy who started it and who raises the money. And I am so humbled by how bad I am now. If you learned something today, please share it with us! And actually, my model ended up working really well, but I was basically threatened that Id be fired if I ever did it again. His practice also focuses on elements such as diet, sleep, exercise, and, physiological aspects that promote So there are lots of benefits to fasting. What a complete and total travesty. When I finished residency, if you looked at a blood panel of mine, you would never imagine that I was a 33-year-old. And then the evening would be going to the gym for sparring. Dr. Peter Attia is the founder of Attia Medical PC. Dr. Peter earned his M.D. And you say, I die.. Dr. Peter Attia is a medical doctor specializing in health, longevity and preventive medicine. He has since been mentored by some of the most experienced and innovative lipidologists, endocrinologists, gynecologists, sleep physiologists, and longevity scientists in the United States and Canada. Marion Nestle notes the Arnold's working relationship with a National Restaurant . So I know Ive got the time to get better and better. A surgeon who developed metabolic syndrome himself despite the fact that he ate well and exercised often, Attia realized that our understanding of these important health issues may not actually be correct. Comments are welcomed and encouraged. So I abandoned that one on my own. Steven LEVITT: If I were really sick, Peter Attia is who Id want for my doctor. But I loved the benefits of nicotine.. Readdressing Dietary Guidelines - Dr. Peter Attia. Which doesnt necessarily undo or undermine the results of that. So how can we combat Type 2 diabetes? And then take a little step further, and you reach neurodegenerative disease, of which Alzheimers disease is far and away the most common and also the most rapidly increasing. And then you have to have a third project, which is like 75 percent done. So I dont really chew it that much anymore, just out of sheer laziness. Meet Peter Attia, the Longevity Doctor That Detected Chris Hemsworth's "Biggest Fear" An Alzheimer's gene threatens the actor's healthspan, but Attia has a plan to fight back. All rights reserved. He also. ATTIA: What an obnoxious idiot I was. He is the Co-founder and Chief Medical Officer of the fasting app. It turns out that our bodies perform a lot of glucose disposal when we sleep, so sleep is incredibly important for preventing glucose from building up in our bloodstreams. Anonymous comments will be deleted. Studying studies: relative risk vs. absolute risk. And theres actually literature thats been done where you can inoculate healthy volunteers. And then the key was that they said, If you ever sleep longer than three hours, you ever do one full night of sleep, your body resets completely and youve lost it.. He is of Coptic Egyptian descent. I mean, not even hard to figure out if youre willing to do randomized experiments. And caffeine blocks that. ATTIA: So ketosis is arguably one of the most important, if not the most important, metabolic adaptation that allowed our species to survive, because our brains are so dependent on glucose. Dr. Peter trained for five years at the, in general surgery, where he was the recipient of several prestigious awards, including Resident of the Year. Hes spent the last few years being mentored by the top medical scientists and now hosts. I mean, I probably wish I had been a bit more introspective a bit sooner. My med school was at Stanford. Those are the three biggest causes of death heart disease, cancer, and Alzheimers. I hope you loved this episode as much as I did. You remember what Im talking about? And I think most people do find a lot of benefit from it. Explore the list of the most recommended book titles suggested by Peter Attia . Yesterday, I just finished a three-day fast. So given those two facts, I would love it if there was an unbelievable amount of attention paid to: what will our next response be? And then after school, I would get home and then do another 90 minutes of work on the heavy bag, speed bag, double end bag in my basement, coupled with more anaerobic training. My practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease), while simultaneously improving healthspan (quality of life). is part of the Freakonomics Radio Network, and is produced by, and Stitcher. Last week, Peter Attia wrote a criticism of Game Changers, where he presented the argument (long repeated him) that nutritional epidemiology is fundamentally flawed. ATTIA: Yeah, I mean, most of these viruses are actually benign enough. LEVITT: So can you talk about ketosis a little bit and what that means? LEVITT: One of the things that really bothers me about myself is that I can fall asleep anywhere, anytime. But what was it? Airplane versus subway? So I was probably averaging 28 hours of sleep a week when I was in residency. And we do that a ton. And they mightve spent the last 20 of those years in an unbelievable state of misery. And I want you to interrupt me every time you have a question.. What happened to @DMSabatini. If you pay any attention to history, we will have another pandemic that will involve yet another virus. Im so grateful to him for taking the time to join me here on, Healthspan has three pieces, right? It also impairs senescent cells or more likely impairs the secreting factors that are made by senescent cells. And tell us about the longest period of time you ever spent in ketosis. Wouldnt you like to live longer? So the former is one molecule of something called glucose and one of fructose bound together. To listen ad-free, subscribe to Stitcher Premium. When it comes to reversing the effects of Type 2 diabetes and preventing further chronic health problems, sleep is essential. 200mg is relatively minor, but he supplemented for the sake of avoiding muscle cramps. And look, if you had to choose between someone having your dads life and he dropped dead tomorrow, lets say he had a heart attack on a run tomorrow, Id still take that over the person who lives to be 100 but spent 20 years in a state of decline. Whats so good about being in ketosis? And by listening to this guy talk about subjects where I have a different point of view, hes sharpening my point of view and sometimes changing my point of view. makes a complete mockery of what sexual harassment is and is not. It also has a significant effect in terms of fat oxidation. His practice deals extensively with nutritional interventions, exercise physiology, sleep physiology, emotional and mental health, and pharmacology to increase lifespan (delay the onset of chronic disease) while simultaneously improving healthspan (quality of life). But I still stand by the benefits of nicotine. Thank you so much for joining me today! Thats actually a billion dollar question. By Sydney Bueckert, NASM CPT, CES, FNS, GPT November 23, 2022 Autophagy is, as its name implies auto is self, phagy is eating so its when these cells eat themselves. LEVITT: I cant think of many people who have reflected on their life as effectively as you have especially successful people and been able to rewrite it. But I think every once in a while, its good to make them a little uncomfortable and stretch them a little bit. Then a 90-minute nap in the middle of the day is restorative and additive to what you get at night. Where did this drive come from? I dont know if you remember the first time we met, but we were at dinner and it must have been just after your birthday because you were glowing and you said, Oh my God, I got the best birthday present ever from my wife. And just to jog your memory, shed given you some kind of equipment that allowed you to prick your finger and do blood tests. And during all of this intentional exercise, Dr. Peter has one thing in mind: his Centenarian Olympics. Youll be able to read more about this in Dr. Peters book when it comes out, but for now, I can tell you that the Centenarian Olympics is a series of activities that Dr. Peter wants to be able to do when he turns 100. I actually find a fasting sleep to be some of the most amazing because Im watching this plummeting temperature, rising heart rate variability, falling heart rate, all of those really valuable things. , I think there [are] basically three ways that we can approach dealing with this: One of these is through psychotherapy, pharmacotherapy, and then behavioral therapy, which Im an overwhelming proponent of in particular a type of behavioral therapy called Dialectical Behavioral Therapy or DBT. , My training is very specific, but now it is fundamentally organized around four pillars: Stability, strength, mitochondrial or aerobic efficiency, and anaerobic performance. , Those four main pillars focus on the different areas Dr. Peter wants to maintain good health even into old age. that was typically done by putting your finger in the air and looking at which way the wind blows. And maybe I would also say how ineffective our medical system has been more generally with Covid. , where his research focused on immune-based therapies for melanoma. Im the only one left of anyone I knew when I was young who is still alive and functioning, which is obviously the only curse that comes with longevity. But my hunch is, youd know better than me, is that for things like influenza, we actually dont even know the answer, even though weve had 100 years to be thinking about that. Sign-up (free) to receive the5 Tactics in my Longevity Toolkitdelivered by email as a 5-day course. Attia has a chapter giving advice in Tim Ferriss' book Tools of Titans. One half of all Americans are on that spectrum. , So how can we combat Type 2 diabetes? Im actually going to tuck them underneath my lip like chewing tobacco and let it just ease out and keep me going.. And I missed that routine once in four years. So my guess is, theres some measure around helping them become better thinkers. The short answer is, its never been deemed interesting enough to do the studies, which is great news to me, because Im 100 percent convinced this is a knowable set of answers, but someone just has to do the research. LEVITT: And so why? Put simply, Type 2 diabetes is what happens when your body cannot dispose of the amount of glucose youre consuming. Enjoy this content? Do you recognize that in yourself? Why werent we immediately engaging in a whole bunch of experiments that would very rapidly get us answers to questions that would enable us to decide what to do? I could basically, within two weeks, turn you into an almost-diabetic by sleep depriving you. , Almost anything youre going to eat is going to come with something thats going to slightly raise your temperature. Its about exercising intentionally. But I just decided death would be welcome. and . Peter Attia talks with Steve Levitt about the problem with immortality, what's missing from our Covid response, and why nicotine is underrated. To improve sleep, Peter Attia takes phosphatidylserine, magnesium and a supplement called Doc Parsley's Sleep Remedy (a company in which Attia invested), comprising of vitamin D, niacin, magnesium (150 mg), and a blend of tryptophan, GABA, phosphatidylserine, theanine, 5-HTP and melatonin. There are papers that have talked about and theorized that theres probably a 15-year extension that is plausible if everything is done right. All contents Freakonomics. What type of a mask really matters? Peter Attia, MD, is the President and co-Founder of the Nutrition Science Initiative (NuSI). Was doing to my health youve come to appreciate, in recent years, the less I agreed with.! When its been de-risked physician focused on immune-based therapies for melanoma where theres really! 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